Apalutamide

Apalutamide  Uses

Apalutamide is used to treat men with prostate cancer. This medication belongs to a class of drugs known as anti-androgens (anti-testosterone). It works by blocking the effects of testosterone to slow the growth and spread of prostate cancer.

How to use Apalutamide 60 Mg Tablet

Read the Patient Information Leaflet if available from your pharmacist before you start taking apalutamide and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually once daily. Swallow the tablets whole. Do not cut, chew, or crush the tablets.

If you have difficulty swallowing the tablets whole, you may mix the whole tablets in 4 ounces (120 milliliters) of applesauce. Stir the mixture but make sure not to crush the tablets. Wait 15 minutes, and then stir the mixture again. Wait another 15 minutes and stir the mixture for a third time. Make sure the tablets are well mixed with no solid chunks remaining. Swallow the mixture right away using a spoon. After taking the mixture, rinse the container with 2 ounces (60 milliliters) of water and drink the mixture right away. Repeat the rinse to make sure you take the full dose of the medication. The applesauce/drug mixture should be used within 1 hour of making. Do not store for future use.

The dosage is based on your medical condition and response to treatment. Do not increase your dose or take this drug more often than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets.

Apalutamide  Side Effects

Hot flashes, tiredness, joint pain, nausea, decreased appetite, weight loss, or decreased sexual interest/ability may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This medication may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the results are high.

Tell your doctor right away if you have any serious side effects, including: signs of an underactive thyroid (such as unusual weight gain, cold intolerance, slow heartbeat, constipation).

Treatment with this medication can cause bones and muscles to weaken, which may increase your risk for falls and broken bones. Ask your doctor for details.

This medication may lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection (such as sore throat that doesn't go away, fever, chills, cough).

Get medical help right away if you have any very serious side effects, including: symptoms of a heart attack (such as chest/jaw/left arm pain, shortness of breath, unusual sweating), seizure.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Apalutamide can commonly cause a mild rash that is usually not serious. However, you may not be able to tell it apart from a rare rash that could be a sign of a severe reaction. Get medical help right away if you develop any rash.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Apalutamide  Precautions

Before taking apalutamide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as coronary artery disease, heart failure, recent heart attack), diabetes, high cholesterol, high blood pressure, seizure, increased risk for seizure (such as brain injury, stroke, brain tumor).

Since this medication may rarely cause seizures in some people, ask your doctor if you should avoid activities where a sudden loss of consciousness may cause serious harm to you or others.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

This medication should not be used by women, especially during pregnancy or breast-feeding. It may harm an unborn or breast-feeding baby. Consult your doctor for more details.

 Older adults may be at greater risk for falls while using this drug.

Men who are sexually active with a pregnant woman must use a condom during treatment and for 3 months after stopping treatment. Men with female partners of childbearing age should use reliable forms of birth control during treatment and for 3 months after stopping treatment. If your partner becomes pregnant or thinks she may be pregnant, tell the doctor right away. Do not donate sperm during treatment and for at least 3 months after stopping treatment.

Apalutamide  Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Apalutamide can speed up the removal of other medications from your body, which may affect how they work. Examples of affected drugs include artemether-lumefantrine, azole antifungals (such as isavuconazonium, voriconazole), boceprevir, cobicistat, lurasidone, nifedipine, ranolazine, rilpivirine, telaprevir, certain drugs for hepatitis C (such as asunaprevir, daclatasvir, ledipasvir, sofosbuvir), among others.

Note:  We strongly encourage you to talk with your health care professional about your specific medical condition and treatments. The information contained in this website is meant to be helpful and educational, but is not a substitute for medical advice.

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