Why are these drugs?
Entecavir is used to treat chronic (long-term) hepatitis B infection (liver edema caused by a virus) in adults and children 2 years of age or older who have liver damage. Entecavir is in a class of drugs called nucleoside analogs. It works by decreasing the amount of hepatitis B virus (HBV) in the body. Entecavir does not treat HBV and cannot prevent complications of chronic hepatitis B, such as cirrhosis of the liver or liver cancer. Entecavir does not prevent the spread of HBV to other people.
How should this medicine be used?
Entecavir is available as a tablet and solution (liquid) for oral administration. It is usually taken once a day on an empty stomach, at least 2 hours after a meal and at least 2 hours before your next meal. Take entecavir at the same time every day. Follow the directions on the prescription label carefully and ask your doctor or pharmacist to explain any part you don't understand. Take Entecavir exactly as directed. Do not take more or less of it, or take it more often than your doctor prescribed.
To use entecavir oral solution, follow these steps:
Hold the spoon that came with your medicine upright and slowly fill it with entecavir solution up to the mark for your dose.
Hold the spoon with the volume markings facing you and make sure the top of the liquid is at the level of the mark for your dose.
Swallow the medicine directly from the measuring spoon. Do not mix the medicine with water or any other liquid.
Rinse the spoon with water after each use and allow it to air dry.
Put the spoon in a safe place where it won't get lost because you will have to use it every time you take your medicine. If you lose your dosage spoon, call your doctor or pharmacist.
Other uses for this medication
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking entecavir,
Tell your doctor and pharmacist if you are allergic to entecavir or any other medicines, or any of the ingredients in entecavir tablets or oral solution. Ask your pharmacist for a list of ingredients.
Tell your doctor and pharmacist what other prescription and nonprescription drugs, vitamins, dietary supplements, and herbal products you are taking or planning to take. Be sure to mention the medicines listed in the IMPORTANT WARNING section and any of the following: aminoglycoside antibiotics such as amikacin, gentamicin, streptomycin, and tobramycin (tobi); or medicines to prevent rejection of the transplanted organ, such as cyclosporine (Gengraf, Neoral, Sandimmune) or tacrolimus (Prograf). Your doctor may need to change the doses of your medications or monitor you closely for side effects.
Tell your doctor if you have had a liver transplant (surgery to replace a diseased liver) or if you have or have ever had kidney disease.
Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking entecavir, call your doctor. Do not breast-feed while you are taking entecavir.
If you have surgery, including dental surgery, tell your doctor or dentist that you are taking entecavir.
What special dietary instructions should I follow?
If your doctor tells you otherwise, continue with your normal diet.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it's almost time for your next dose, skip the missed dose and continue with your normal dosing schedule. Do not take a double dose to make up for the missed dose.
What side effects can this medicine cause?
Entecavir can cause side effects. Tell your doctor if this symptom is severe or persists:
Some of the side effects can be serious. If you experience any of the symptoms listed in the IMPORTANT WARNING section, call your doctor immediately.
Entecavir can cause other side effects. Call your doctor if you have any unusual problems while using this medication.
If you experience serious side effects, tell your doctor.
What should I know about storing and disposing of this medication?
Keep this medicine in the container it was in, tightly closed, and out of the reach of children and pets. Store it at room temperature and away from excess heat, light, and moisture (not in the medicine cabinet in the bathroom or near the kitchen sink).
It is important to keep all medicines out of the reach of children, as many containers (for example, weekly pills and tablets for eye drops, creams, patches and inhalers) are not child resistant and can be easily opened by young children. To protect young children from poisoning, always close the protective caps and immediately place the medication in a safe place - up and down, out of sight and reach.
Unnecessary medications should be disposed of in a special way so that pets, children and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to get rid of your drugs is through a drug take-back program.
In case of emergency / overdose
In case of overdose, call your doctor or ambulance. If the victim is unconscious, has a seizure, breathing problems, or cannot be woken up, call emergency services immediately.
What other information should I know?
Don't let anyone else take your medication. Ask your pharmacist any questions about prescription refills.
It is important for you to keep a written list of all prescription and non-prescription (over-the-counter) medicines you take, as well as any foods such as vitamins, minerals, or other dietary supplements. You should take this list with you every time you visit your doctor or go to the hospital. It is also important information to carry with you in case of emergencies.
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