Hepcinat и Natdac (Sofosbuvir Daclatasvir)

Dosage form and composition of Hepcinat and Natdac

The drug Hepcinat and Natdac - Hepcinat is a combination of two active substances - sofosbuvir (400 mg in one tablet) and ledipasvir - aimed at eliminating the hepatitis C virus, which causes the same disease of the first genotype in chronic form. The drug is produced in tablet form, each tablet is covered with a coating that is soluble in gastric juice.

As part of Natdak, daklatasfir (60 mg in each tablet) acts as an active substance. It is also available in tablet form. Natdak's action is directed directly at the hepatitis C virus, which is located in the liver cells. Under the influence of this drug, infected cells of the virus can no longer enter the bloodstream. Thus, the drug prevents their spread throughout the human body.

Indications and uses of Hepcinat and Natdac

Both described drugs constitute a therapeutic drug complex, which is prescribed for hepatitis C of the first and fourth genotypes of the chronic form. These drugs are also prescribed if the patient has a diagnosed cirrhosis of the liver, when all previous therapeutic methods have not yielded results.

Medications are taken, one tablet of each, once a day, preferably at the same time.

It is recommended to take hepcinate with food, drink it with a little water. Unlike it, Natdak can be taken without being tied to the process of food intake.

The tablets should not be chewed, bitten, or sucked. Their very unpleasant, pungent bitter taste can induce vomiting, which will lead to the need to take the dosage again.

If the time of admission was missed, the pills have not been drunk and less than 16 hours have passed, you can take one pill for each drug. If the time period has exceeded the 17 hour period, you should wait for the usual time of admission, but in no case increase the dosage.

Side effects

Complex therapy with these medications can cause negative reactions, especially with increasing dosages or non-compliance with the regimen and rules for taking pills of this category (antihepatic).

Such negative symptoms will include:

• General weakness throughout the body, nausea;
• Night sleep disturbances;
• Disturbance and complete loss of appetite, weight loss;
• Increased irritability;
• Headache, dizziness;
• Soreness in the epigastric region;
• Dermatological manifestations (dryness and flaking of the skin);
• Intestinal disorders.

All this can manifest itself only if the patient does not comply with the doctor's prescriptions or suffers from an increased level of sensitivity to the active substances of these drugs.

Contraindications and precautions

There are no contraindications as such for this complex drug therapy. It is important not to take medications without clear instructions and prescriptions from your doctor. For pregnant and lactating mothers, be sure to inform your gynecologist about the prescription of these medications before you start taking them. It is recommended to completely stop breastfeeding for the period of treatment.

Both drugs are not interchangeable, but complement each other's action in the fight against the hepatitis C virus. Therefore, they are not allowed to be taken separately. The course of treatment is carried out only in combination.