0
Products in the cart
Total:
Information block example
Currency
English Support
Request a call
Working hours:
Пн-Пт 9:00—23:00;
Сб-Вс 10:00-20:00

Revolade 50mg

Revolade 50mg (Eltrombopag)

Revolade 50mg  isan anticancer medication which is;

Indicated for the treatment of patients having Severe aplastic Anemia

• First line treatment of severe aplastic Anemia

• Treatment of refractory severe aplastic Anemia

Indicated for the treatment to stimulate the growth and development of platelets in the bone marrow

Primarily indicated for the treatment of patients having reduced platelet counts due to chronic hepatitis C virus infection

 

Feature
Brand name:
Revolade
Active substance:
Eltrombopag 50mg
Packaging:
14 Tablets
Product form:
Tablet
Strength:
50mg
In stock
Active substance: Eltrombopag
0 $
Available options:
Amount:
To wishlist
Compared
Consulting:+91(994)0472902
Description

DESCRIPTION

Eltrombopag is sold under the brand name Revolade and it is a man-made form of a protein that increases production of platelets (blood-clotting cells) in your body.
Revolade 50mg  can reduces the risk of bleeding by increasing platelets in your blood.
Revolade 50mg  which is used asprescription drug under the guidance of the medical practioners

INDICATION

Revolade 50mg  isan anticancer medication which is;

Indicated for the treatment of patients having Severe aplastic Anemia

• First line treatment of severe aplastic Anemia

• Treatment of refractory severe aplastic Anemia

Indicated for the treatment to stimulate the growth and development of platelets in the bone marrow

Primarily indicated for the treatment of patients having reduced platelet counts due to chronic hepatitis C virus infection

MECHANISM OF ACTION

Eltrombopag consist of class of drugs known as thrombopoietin (TPO) receptor agonists. A class of drugs is a group of medications which work in a same way.

Eltrombopag mechanism by raising cells in your bone marrow and causes these cells to make more platelets. This effect reduces your risk of bleeding.

PHARMACOKINETICS

 Absorption:
High plasma concentration is 2-6 hours
Distribution:
Maximum human plasma protein bounding is >99% and in blood plasma level is 50% to 79%
Metabolism:
generally metabolised via cleavage, oxidation and conjugation with glucuronic acid.
Elimination:
Revolade 50mg  eliminated mainly via feces 59%, along with 31% via renally excreted
Revolade 50mg  Half-life for healthy patients is 21-23 hours and idiopathic thrombocytopenic purpura is 26-35 hours.

DOSAGE MANAGEMENT

• The usual dose for Chronic Hepatitis C-associated Thrombocytopenia is 25 mg PO qDay. Dose is managed in 25 mg accretion q2weeks PRN to attain target Plt needed to start/control antiviral therapy with pegylated interferon and ribavirin; not to exceed 100 mg/day
• Severe Aplastic Anemia :
1.First-line therapy :
When combination with standard immunosuppressive treatment, for patients with serious aplastic Anemia (SAA)
The usual dose for severe Aplastic Anemia: 150 mg PO qDay for 6 months
Avoid taking of more than starting dose; total duration is 6 months
2.Refractory SAA :

In this condition the drug given who fail to respond enough to at least 1 before immunosuppressive therapy
The usual dose for Refractory SAA: 50 mg PO qDay
• The recommended dose for Chronic Immune Thrombocytopenia is 50 mg PO qDay Adjust dose to manage and control platelet count (Plt) >50 x 10^9/L to reduce the risk of bleeding; not to exceed 75 mg/day

PRECAUTION

• The drug Revolade 50mg  may have high risk of severe and probably life-threatening hepatotoxicity; monitor liver function before and during treatment
• While receiving the drug, if patient with hepatic impairment (Child-Pugh Class A, B, C) initiates therapy for first- line treatment of severe aplastic Anemia, reduce initial dose
• When treatment, If the patients have cataracts, do not use the drug due to the Revolade 50mg  effects cataracts and make the condition worse.
• Avoid the Revolade 50mg  while the patients have myelodysplastic syndrome (MDS), will increases the risk of death.
• While on treatment with drug Revolade then Portal vein thrombosis reported in patients with chronic liver disease.

SIDE EFFECTS

Common side effects of Revolade 50mg  :
• Headache
• Cough
• Loss of appetite
• Flu
• Reduced red blood cells
• Diarrhoea
• Nausea
• Fever
• Weakness
Serious side effects of Revolade 50mg  :
• Swelling of legs
• Abdomen swelling
• Confusion
• Chest pain
• Dyspnea
• Cloudy vision
• Urine in dark colour
• Yellowing of your skin
• Sensitivity to light
• Seeing circles around lights

DRUG INTERACTION

When Revolade 50mg  interacts with Cholesterol-reducing drugs like atorvastatin, fluvastatin, rosuvastatin, pravastatin, and simvastatin, pitavastatin combination with Revolade 50mg . Have high side effects can contains muscle pain. The doctor may decrease the dosage of your cholesterol drugs.

When Revolade 50mg  interactionwithezetimibe, glyburide, Olmesartan, repaglinide, valsartan, imatinib, irinotecan, lapatinib, methotrexate, mitoxantrone, Bosentan, sulfasalazine, and topotecan irinotecan will increase the side effects. Hence thedoctor may decrease your dosage of these drugs if necessary.

Antacids, vitamins, or supplements which involves Ca, Al, Fe, Se, Zn, or Mg concomitant use with Revolade 50mg . To stop interactions, then take Revolade two hours before or four hours after administrating any of these products.

PREGNANCY

Pregnancy category is C
Safety of drug during pregnancy is not established.

 LACTATION

During breast feeding, avoid using of drug Revolade 50mg

STORAGE

Store at room temperature 20°C and 25°C.

MISSED DOSE

If the missed dose occurs, patients must consult with medical practitioner and follow the instructions given by them.

Therefore, missed dose should be avoid and follow the regular dosing schedule.

Feature
Brand name
Revolade
Active substance
Eltrombopag 50mg
Packaging
14 Tablets
Product form
Tablet
Strength
50mg
Revolade 50mg отзывы
Add a comment
0

We use cookies to make the site better for you! Note: We strongly encourage you to talk with your health care professional about your specific medical condition and treatments. The information contained in this website is meant to be helpful and educati
MEDICAL DISCLAIMERAll the contents present on the website are solely for informational purposes. Thereby, the information on the website isn’t meant to be a substitute for professional medical advice, treatment, and/or diagnosis. Please seek professiona